PD23 - Decision points for boiled egg challenges in Greek children with sensitisation to egg proteins

نویسندگان

  • Marianna Tziotou
  • Maria Psomiadou
  • Anna Pananaki
  • Anastasios P Konstantinopoulos
  • Dimitrios Koutsalitis
  • Dimitrios Karantoumanis
  • Anastasia Karamouza
  • Eirini Roumpedaki
  • Stavroula Giavi
  • Emmanouil Manousakis
  • Nikolaos Douladiris
  • Nikolaos G Papadopoulos
چکیده

Introduction Decision points based on food-specific IgE antibody concentrations have been proposed and are used in the clinic, in order to predict reactivity to foods and reduce the number of high risk food challenges. In the process of screening for eligibility in a study, we started carrying out open food challenges to boiled egg in children with sensitization to egg proteins, independent of their skin reactivity and specific IgE concentrations. In several occasions, the expected cut-off points were not confirmed. Furthermore, cut-off points have been evaluated in children with clinical indications of allergy and not in those who are only sensitized. Therefore, we hypothesized that decision points for this population may need to be reevaluated.

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عنوان ژورنال:

دوره 4  شماره 

صفحات  -

تاریخ انتشار 2014